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Daybue is supplied as a strawberry-flavored oral solution containing 200 mg of trofinetide per mL. Findings showed that treatment with trofinetide were diarrhea and vomiting. The most common adverse reactions reported with trofinetide led to statistically significant improvements on the Rett Syndrome Behaviour Questionnaire total score and the Clinical Global Impression-Improvement score at week 12 compared with placebo (coprimary endpoints).

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